成都市0～6岁儿童25-羟维生素D水平调查

目的:了解成都市儿童维生素D的营养状况。方法:对来医院儿童保健科门诊进行常规体检的0～6岁701例儿童采用酶联免疫法进行血清25-(OH)D检测。结果:25-(OH)D的平均测定值为(68.60±1.29)nmol/L,25-(OH)D缺乏及严重缺乏的为226例,占32.24%;25-(OH)D水平不足的为237例,占33.811%;水平充足(合适水平)的为238例,占33.95%,前两者占总人数的66.05%。男性和女性血清25-(OH)D水平差异无统计学意义(P>0.05),但25-(OH)D水平随着年龄增高而呈下降(P<0.01)。血清25-(OH)D水平夏秋季显著高于春冬季节(P<0.05)。结论:成都市0～6岁儿童25-(OH)D水平低下,应增加该地区儿童的维生素D摄入量及加强户外活动,尤需重视3～6岁的儿童及冬春季节维生素D的补充。

Investigation on 25-hydroxyvitamin D levels in children aged 0-6 years old in Chengdu city

Objective:To understand the nutritional status of vitamin D in children in Chengdu city.Methods:ELISA was used to detect serum levels of 25-hydroxyvitamin D in 701 children who received physical examination in child health care department of the hospital.Results:The mean value of 25-hydroxyvitamin D was(68.60±1.29) nmol/L,226 children were found with deficiency and severe deficiency of 25-hydroxyvitamin D,accounting for 32.24%;237 children were found with insufficiency of 25-hydroxyvitamin D,accounting for 33.81%;238 children were found with sufficiency of 25-hydroxyvitamin D,accounting for 33.95%,the children with deficiency,severe deficiency,and insufficiency of 25-hydroxyvitamin D accounted for 66.05%.There was not statistically significant difference in serum 25-hydroxyvitamin D level between boys and girls(P>0.05),but serum 25-hydroxyvitamin D level decreased with age(P<0.01).The levels of serum 25-hydroxyvitamin D in summer and autumn were statistically significantly higher than those in spring and winter(P<0.05).Conclusion:The serum levels of 25-hydroxyvitamin D in children are low in Chengdu city.Additional vitamin D supplementation and outdoor activities are necessary in this area.Vitamin D supplements are important for children aged 3-6 years old and in spring and winter.