瑞芬太尼全身麻醉对剖宫产产妇及新生儿的影响研究

目的探讨瑞芬太尼全身麻醉对剖宫产产妇及新生儿的影响。方法选择本院收治的足月择期行剖宫产的产妇54例，随机分为A组（瑞芬太尼全麻组）和B组（普通全麻组）各27例。对比分析两组产妇的血流动力学变化、苏醒时间以及新生儿的Apgar评分情况。结果插管、拔管时，A组产妇的HR、MAP、SBP、DBP值明显低于B组（P〈0．05），且A组产妇拔管时有2例出现低血压；但插管前、切皮时，两组各项血流动力学参数比较差异无统计学意义（P〉0．05）。A组产妇的苏醒时问为（5．4±3．2）min，明显短于B组的（13．2±5．2）min（P〈0．05）。两组新生儿的Apgar评分比较差异无统计学意义（P〉0．05）。结论瑞芬太尼的麻醉诱导平稳，产妇苏醒迅速，且对新生儿无明显影响，值得临床广泛推广。

The impact study of remifentanil general anesthesia on puerpera after caesarean section and neonate

Objective To discuss the impact of remifentanil general anesthesia on puerpera after caesarean section and neonate. Methods Fifty-four puerperae in full term for cesarean delivery admitted into our hospital were selected and evenly divided into group A （remifentanil general anesthesia group） and group B （general anesthesia group） in random. The hemodynamic changes, wake-up time, and Apgar score in neonate were compared and analyzed in both groups. Results During intubation and extubation, the values of heart rate （HR）, mean arterial pressure （MAP）, systolic blood pressure （SBP）, and diastolic blood pressure （DBP） in group A were much lower than those in group B （P 〈 0.05）. In addition, there were 2 puerperae presenting with hypotension on tube drawing in group A. However, before intubation and during skin incision, there were no significant differences in parameters of hemodynamic changes in the two groups （P 〉 0.05）. The wake-up time of puerperae in group A was （5.4±3.2） min, which was remarkably shorter than the （13.2±5.2） rain in group B （P 〈 0.05）. The Apgar scores in neonates from both groups were not significantly different （P 〉 0.05）. Conclusion The caesarean section anesthetized by remifentanil is stable with some advantages of quick maternal awakening and no significant impact on neonate, which is worthy of wide extension in clinic.