头疼患者脑脊液中常量及微量元素的变化

用等离子光量计检测了87例头疼患者和66例非头疼患者脑脊液(CSF)中4种必需常量元素:磷、钠、钙、镁;10种必需微量元素:铁、锶、铜、镍、锌、钒、铬、锰、钼、钻;12种其它微量元素:铅、钛、铝、镧、钡、硅、铈、镱、钪、银、镉、硼共26种元素的含量。与非头疼患者CSF中有关元素含量相比,头疼患者CSF中含量显著升高或非常显著升高的有镍(P<0.05),铈、镱、钪、银(P<0.01)等8种;显著或非常显著降低的元素有锰、铁(P<0.05)、磷、钠、钙、镁、锶、锌,铝、钡、硼(P<0.01)等11种;其余几种元素未见明显差异。结果提示头疼患者CSF中伴有多种元素含量的改变。其机理和意义有待进一步探讨。

Changes in Contents of Major and Trace Elements in Cerebrospinal Fluid of Patients with Headache

The in variation contents of four types of indispensable major elements: Phosphorus (P), Sodium (Na), Calcium (Ca), and Magnesium (Mg); ten types of indispensable trace elements. Iron (Fe), Strontium(Sr), Copper(Cu), Nickel (Ni), Zinc (Zn), Vanadium (V), Chromium (Cr), Manganese (Mn), Molybdenum (Mo), and Cobalt (Co), and twelve types of other elements: Lead (Pb), Titanium(Ti), Aluminium(A1), Lanthanum(La), Barium(Ba), Silicon(Si), Cerium(Ce), Ytterbium(Yb), Seandium(Sc), Silver (Ag), Cadminm (Cd), and Boron(B) in cerebrospinal fluid(CSF) was measured on 87 patients suffering from headache and 66 patients without headache. A significant increase in Ni (P<0.05), Ce, Yb, Sc, Ag, and B (P<0.01); a significant decrease in Fe (P<0.05), Na, Ca, Mg, Sr, Zn, Al, and Ba (P<0.01) and no change in P, Cu, V, Cr, Mn, Mo, C, Pb, Si, Ti, La and Cd were found in cases suffering from headache in comparison with those in headache-free eases. The results indicate that variation in many chemical elements is associated with headache- bearing patients. Its mechanism and significance remain to be studied.