| 肝硬化患者血清胆固醇总胆汁酸检测意义探讨 |
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| 引用本文： | 王瑜,许海生,马玉娥.肝硬化患者血清胆固醇总胆汁酸检测意义探讨[J].医药论坛杂志,2006,27(4):42-43. |
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| 作者姓名： | 王瑜 许海生 马玉娥 |
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| 作者单位： | 安阳市第五人民医院,安阳市,455004 |
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| 摘 要： | 目的探讨检测肝硬化患者血清胆固醇(CHO)及总胆汁酸(TBA)的临床意义。方法前瞻性研究85例肝硬化患者和68例健康者的血清胆固醇及TBA水平。结果肝硬化组血清CHO水平显著低于对照组(P<0.05),而TBA水平显著高于对照组(P<0.01);CHO在Ch ild-Pugh C级中最低,与A级和B级相比有显著性差异(P<0.05);TBA在A级,B级和C级间均存在着显著性差异,且随着肝功能Ch ild-Pugh分级的增高而增高。结论TBA能敏感地反映肝硬化的程度,联合检测CHO有助于病情的判断。
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| 关 键 词： | 肝硬化 总胆汁酸 胆固醇 肝功能 |
| 文章编号： | 1672-3422(2006)04-0042-02 |
| 收稿时间： | 09 1 2005 12:00AM |
| 修稿时间： | 2005年9月1日 |
Clinical Significance of Serum Cholesterol and Total Bile Acid in Patients with Hepatocirrhosis |
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| WANG Yu,XU Haisheng,MA Yue.Clinical Significance of Serum Cholesterol and Total Bile Acid in Patients with Hepatocirrhosis[J].Journal of Medical Forum,2006,27(4):42-43. |
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| Authors: | WANG Yu XU Haisheng MA Yue |
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| Abstract: | Objective To evaluate the clinical significance of serum cholesterol(CHO) and total bile acid(TBA) in patients with hepatocirrhosis.Methods The serum levels of CHO and TBA were prospectively studied in 85 patients with hepatocirrhosis and 68 healthy persons.Results Serum CHO level was significantly lower in cases with hepatocirrhosis than that of control group(P<(0.05)),but serum TBA level significantly higher(P<0.01).Serum CHO level was the lowest in Child-Pugh C grade and was significantly different between C grade and A grade as well as B grade(P<(0.05)). Serum TBA level was significantly different among A,B and C grade,it increased with the liver function of Child-Pugh grade.Conclusion Serum TBA level can sensitively reflect the degree of hepatocirrhosis,the tests of TBA and CHO are helpful to confirming the state of patients. |
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| Keywords: | Hepatocirrhosis Total bile acid Cholesterol Liver function |
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