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CYTOCHEMICAL CLASSIFICATION OF ACUTE LYMPHOBLASTIC LEUKEMIA IN CHILDREN
Authors:Y X Gu  Y F Cui  X T Liu  Y Bai  Z X Tan  D F Zhang  S G Lu
Abstract:By acid phosphatase (ACP), 5-nucleotidase (5'N)activities and PAS reaction patterns, the classifica-tion of 31 acute lymphoblastic leukemia (ALL) cases(including 5 adult cases) were studied cytochemical-ly. The results indicated that 16% 0f the cases wereT-ALL, while 84% were nonTnonB-ALL. The resultsof monoclonal antibody method and E-rosette me-thod were in good accordance with the cytochemicalclassification. The various forms of ACP activity patterns,PAS reaction, the relationship between the resultsof monoclonal antibody, E-rosette and cytochemicalmethod and the practical value of ACP activity patterns in the identification of E-rosette negative ALLare discussed.
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