| 精神分裂症患者血清催乳素对电抽搐治疗的反应 |
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| 引用本文： | 端义扬,严志康,刘维莉,施建安,高柏良,沈默宇,薛蕴(艹庄). 精神分裂症患者血清催乳素对电抽搐治疗的反应[J]. 中国神经精神疾病杂志, 1992, 0(2) |
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| 作者姓名： | 端义扬 严志康 刘维莉 施建安 高柏良 沈默宇 薛蕴(艹庄) |
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| 作者单位： | 中国人民解放军第102医院精神科(端义扬，严志康，刘维莉，施建安，高柏良)，中国人民解放军第102医院同位素室(沈默宇)，中国人民解放军第102医院同位素室(薛蕴(艹庄)) |
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| 摘 要： | 对20例女性精神分裂症患者进行ECT-1前30分钟与后5、15、30和60分钟的血清催乳素(PRL)水平测定,其中10例做了ECT-6的复查。结果,ECT-1后PRL水平迅速显著升高,15分钟达最高峰。提示ECT具有急性抗多巴胺和神经阻滞剂样作用。ECT-6前的PRL基础水平较ECT-1前显著升高,ECT-6后PRL的释放较ECT-1显著下降,表明在多次ECT后异常的多巴胺代谢得到了纠正。
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| 关 键 词： | 催乳素 精神分裂症 电抽搐治疗 |
Serum prolactin response to electroconvulsive therapy in patients with Schizophrenia. |
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| Duan Yiyang,et al Department oj Psychiatry,th Hospital. PLA. Ch-angzhou .. Serum prolactin response to electroconvulsive therapy in patients with Schizophrenia.[J]. Chinese Journal of Nervous and Mental Diseases, 1992, 0(2) |
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| Authors: | Duan Yiyang et al Department oj Psychiatry th Hospital. PLA. Ch-angzhou . |
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| Affiliation: | Duan Yiyang,et al Department oj Psychiatry,102th Hospital. PLA. Ch-angzhou 213003. |
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| Abstract: | Serum prolactin (PRL) levels were determined in 20 of schizophrenic females 30 min before and 5, 15, 30 and 60 min after the first electroconvulsive therapy (ECT-1). The levels of PRL in 10 of the 20 patients were reexamined before and after the sixth electroconvulsive therapy (ECT-6). There was a rapid increase in serum PRL and the mean maximum level was obtained at 15 min after ECT-1. It was indicated that ECT had an acute anti-dopaminergic, neuro-leptic-like action. Baseline PRL level was significantly higher before ECT-6 than before ECT-1, but PRL release,was significantly lower after ECT-6 than ECT-1. It seems to indicate that the abnormal dopamine matabclism is normalized after a series of ECT. |
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| Keywords: | Prolactin Schizophrenia Electroconvulsive therapy |
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