脉络宁联合地塞米松及胞磷胆碱钠治疗突发性耳聋的疗效观察

目的 探讨脉络宁联合地塞米松及胞磷胆碱钠治疗突发性耳聋的疗效.方法 53例突发性耳聋患者,分为治疗组27例和对照组26例.治疗组给予脉络宁注射液20 ml、地塞米松5 mg及注射用胞磷胆碱钠1.0 g加入5% 葡萄糖注射液或0.9%氯化钠溶液250 ml静脉滴注,1次/d;对照组给予脉络宁注射液20 ml加入5%葡萄糖溶液250 ml静脉滴注,1次/d,均10 d为1疗程.结果 治疗组治愈10例,显效12例,有效2例,无效3例;对照组治愈3例,显效5例,有效10例,无效8例.两组治疗效果间差别有统计学意义(u=2.14,P＜0.05).结论 脉络宁联合地塞米松及胞磷胆碱钠治疗突发性耳聋疗效优于单用脉络宁治疗.

Therapeutic Effect of Mailuoning and Dexamethasone and Citicoline Sodium for Sudden Deafness

Objective To observe the effect of Mailuoning and Dexamethasone and Citicoline Sodium on sudden deafness.Methods Totally 53 patients with sudden deafness were divided into two groups.The patients in the trial group (n=27) were given Mailuoning 20ml,Dexamethasone 5mg,Citicoline Sodium 10g in 250 ml solution of 5% glucose or 0.9% normal saline; while those in the control group (n=26) were administered Mailuoning 20ml in 250 ml solution of 5% glucose,by intravenous drip,once a day for 10 days.Results There were in the trial group 10 cases recovered,12 cases remarkably improved,2 cases improved,3 cases unresponded;while in the control group 3 cases recovered,5 cases remarkably improved,10 cases improved,8 cases unresponded,with a significant difference(u=2.14,P＜0.05).Conclusion Therapy of Mailuoning and Dexamethasone and Citicoline Sodium is more effective than single Mailuoning for sudden deafness.