The Acoustic Startle Response in Inbred Roman High- and Low-Avoidance Rats |
| |
Authors: | H. Schwegler P. K. D. Pilz M. Koch M. Fendt R. Linke P. Driscoll |
| |
Affiliation: | (1) Institut für Anatomie, Universität Magdeburg, Leipziger Str. 44, D-39120 Magdeburg, Germany;(2) Zoologisches Institut, Tierphysiologie, Universität Tübingen, Morgenstelle 28, D-72076 Tübingen, Germany;(3) Institut für Nutztierwissenschaften, ETH-Zentrum, Turnerstr. 1, CH-8072 Zürich, Switzerland |
| |
Abstract: | To investigate the emotional reactions of two rat strains selectively bred for good and poor two-way avoidance acquisition (RHA/Verh and RLA/Verh), male animals of both strains were tested in an acoustic startle response test. They received 40 acoustic stimuli followed by 10 electric foot shocks and another 30 acoustic stimuli. RLA/Verh rats showed a significantly higher startle response compared to RHA/Verh animals, indicating a stronger emotional reaction to acoustic stimuli. In addition, the former showed a stronger response to foot shocks. Combined with earlier findings, we conclude that selection for two-way avoidance learning does not result in cognitive defects in the RLA/Verh strain but, rather, in stronger emotional reactions to fearful stimuli. |
| |
Keywords: | Acoustic startle response sensitization amygdala Roman high- and low-avoidance rats |
本文献已被 SpringerLink 等数据库收录! |
|