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紫外分光光度法快速测定乙酰螺旋霉素片的含量
引用本文:张彬,黄燕. 紫外分光光度法快速测定乙酰螺旋霉素片的含量[J]. 中国药品标准, 2004, 5(4): 30-31
作者姓名:张彬  黄燕
作者单位:广州白云山制药总厂,广州,510515
摘    要:目的:采用紫外分光光度法测定乙酰螺旋霉素片中乙酰螺旋霉素的含量.方法:采用pH3.0的盐酸溶液作溶剂,检测波长为230nm.结果:供试品浓度在5~60μg/ml范围内呈良好的线性关系;方法平均回收率:99.8%,RSD=0.2%(n=6).结论:本法简便,灵敏,准确,可作为该制剂的快速测定方法.

关 键 词:紫外分光光度法  乙酰螺旋霉素片  含量测定

Rapid Assay of Acetylspiramycin Tablets by UV Spectrophotometry
Zhang Bin and Huang Yan. Rapid Assay of Acetylspiramycin Tablets by UV Spectrophotometry[J]. , 2004, 5(4): 30-31
Authors:Zhang Bin and Huang Yan
Affiliation:Bai Yun Shan Pharmaceutical Factory, Guangzhou, 510515;Bai Yun Shan Pharmaceutical Factory, Guangzhou, 510515
Abstract:Objective: UV spectrophotometry can be applied to determination in acetylspiramycin tablets. Method: The acetyl-spiramycin is solved by pH3. 0 hydrochloric acid. Detection wavelength of 230nm was specified. Result: A methodological survey pointed out there is a good linearity between 5 to 60 of acetylspiramycin units per ml. The corresponding average recovery is 99. 8%,RSD 0. 2 %(n = 6). Conclusion : The method was found to be simple, rapid, accurate and for determination of acetylspiramycin tablets in its suppositories.
Keywords:UV spectrophotometry  acetylspiramycin tablets  assay
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