认知行为干预对首发精神分裂症患者远期疗效的影响

目的：探讨认知行为干预对首发精神分裂症患者远期疗效的影响。方法：对104例首次发病、经住院治疗处于恢复期的精神分裂症患者随机分为研究组及对照组，研究组54例，对照组50例。研究组给予抗精神病药物治疗的同时给予认知行为干预，对照组只给予抗精神病药物治疗。采用精神分裂症阳性症状量表（SAPS）、阴性症状量表（SANS）、简明精神病评定量表（BPRS）、自知力及治疗态度问卷（ITAQ）和社会功能缺陷筛选量表（SDSS）对两组患者进行2年内康复状态评估。结果：2年末研究组BPRS、ITAQ、SDSS评分明显优于对照组，两组间差异性比较，有显著性意义（P〈0．01）；研究组服药依从性明显优于对照组，两组间差异性比较有显著性意义（P〈0．01）；研究组复发率和再入院率明显低于对照组，两组间差异性比较有显著性意义（P〈0．01）；结论：对首发精神分裂症患者进行认知行为干预，有助于改善精神分裂症残留症状，降低社会残疾程度，对保持精神分裂症患者良好的远期疗效具有积极作用。

The study of cognitive behavior intervention to long period efficacy of first - episode schizophrenic patients

Objective: To explore the effect of cognitive behavior intervention to long period efficacy of first-episode schizophrenic pstients. Methods: 104 first-episode schizophrehrenic patients who has accepted treatment in hospiatal and were in recover period, were randomly divded into study group and control group. Study group accepted both antipsychotic drugs treatment and cognitive behavior intervention, Control group only accepted antipsychotic drugs treatment. Two groups were tested by SAPS, SANS, BPRS. ITAQ,SDSS.Results:2 years later,compared to control group,the study group scored higher on BPRS,ITAQ,SDSS, there was significant difference between the two groups (P< 0.01), compared to controls, study group has good drug compliance (P<0.01); The recur rate (18%)and again in hospital rate(10%)of study group were obviously lower than control group(44%and 36%). There was significant difference between the two groups (P<0.01)Conclusion:To perform aschizophrenia remained symptom,reduce social deformity There was positive role for patients with schizophrenia to keep long pericd efficaly.