自身外周血干细胞移植治疗恶性淋巴瘤一例

本文报道恶性淋巴瘤(ⅡE)患者在接受超大剂量化疗及放疗后,用自身外周血干细胞移植重建其骨髓造血功能获得成功一例。患者血小板数在PBSC移植后8天增至20×10~9/L以上,10天恢复至50×10~9/L以上;白细胞数在PBSC移植后9天增至0.5×10~9/L以上;CT盆腔摄片示肿瘤明显缩小;缓解出院,无症状存活6月余,仍在随访中。提示自身外周血干细胞移植是一种根治恶性肿瘤的安全、有效的辅助疗法。

Treatment of a Case of Malignant Lymphoma by Autologous Peripheral Blood Stem Cell Transplantation

A success in reconstruction of the hematopoietic function of marrow in a case of malignant lymphoma attained by autologous peripheral blood stem cell transplantation after the ultra-high dose chemoradiotherapy was reported. The platelet count of patient was increased to over 20 × 109/L at the eighth day after PBSC transplantation and was recovered to over 50×109/L at the tenth day after PBSC transplantation. The white blood cell count was increased to over 0. 5×109/ L at the ninth day after PBSC transplantation. The pelvic CT-graphy showed reduction in size of the tumor. And then the patient was outhospitalized due to remission,having been surviving for more than 6 months with routine follow-up. It was suggested that the autologous peripheral blood stem cell transplantation could be a safe and effective suplement therapy for radical cure of malignant tumor.