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Dual kidney transplantation after liver transplantation: a good option to rescue a patient from dialysis
Authors:Burcin Ekser  Lucrezia Furian  Nicola Baldan  Alessandra Amico  Luca Fabris  Manuela Lazzarin  Francesco Marchini   Paolo Rigotti
Affiliation:Kidney and Pancreas Transplantation Unit, Department of Surgery and Organ Transplantation, University of Padua;and Division of Nephrology, Azienda Ospedaliera Padova, Padua, Italy
Abstract:Abstract:  Chronic renal failure (CRF) due to calcineurin inhibitor (CNI) nephrotoxicity is one of the most serious side effects influencing mortality and morbidity after liver transplantation (LTx). One way to offer a longer survival and better quality of life to LTx recipients who develop CRF is kidney transplantation, though this is not feasible for all candidates due to the shortage of organs. With changes in the characteristics of the global donor pool, which includes increasing number of elderly donors, both kidneys from one older donor are transplanted into the same adult recipient (dual kidney transplantation, DKT) to offset the lower nephron mass. DKT might be an option after LTx to rescue a patient from dialysis, with consequent survival benefits. We report on two cases of DKT after LTx in patients with CRF who were on dialysis due to CNI nephrotoxicity.
Keywords:dialysis    dual kidney transplantation    expanded criteria donor    liver transplantation    renal replacement therapy
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