Dual kidney transplantation after liver transplantation: a good option to rescue a patient from dialysis |
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Authors: | Burcin Ekser Lucrezia Furian Nicola Baldan Alessandra Amico Luca Fabris Manuela Lazzarin Francesco Marchini Paolo Rigotti |
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Affiliation: | Kidney and Pancreas Transplantation Unit, Department of Surgery and Organ Transplantation, University of Padua;and Division of Nephrology, Azienda Ospedaliera Padova, Padua, Italy |
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Abstract: | Abstract: Chronic renal failure (CRF) due to calcineurin inhibitor (CNI) nephrotoxicity is one of the most serious side effects influencing mortality and morbidity after liver transplantation (LTx). One way to offer a longer survival and better quality of life to LTx recipients who develop CRF is kidney transplantation, though this is not feasible for all candidates due to the shortage of organs. With changes in the characteristics of the global donor pool, which includes increasing number of elderly donors, both kidneys from one older donor are transplanted into the same adult recipient (dual kidney transplantation, DKT) to offset the lower nephron mass. DKT might be an option after LTx to rescue a patient from dialysis, with consequent survival benefits. We report on two cases of DKT after LTx in patients with CRF who were on dialysis due to CNI nephrotoxicity. |
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Keywords: | dialysis dual kidney transplantation expanded criteria donor liver transplantation renal replacement therapy |
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