Population genetics of nine short tandem repeat (STR) loci – DNA typing using the AmpFlSTR Profiler PCR amplification kit |
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| Authors: | M. Hantschel R. Hausmann T. Lederer P. Martus P. Betz |
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| Affiliation: | Insitute of Legal Medicine, University of Erlangen-Nürnberg, Universit?tsstrasse 22, D-91054 Erlangen, Germany Tel. +49-9131-8522272; Fax 9+49-9131-8522274, DE
Institute of Medical Statistics and Documentation, University of Erlangen-Nürnberg, Waldstrasse 6, D-91054 Erlangen, Germany, DE
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| Abstract: | Frequency data for nine short tandem repeat (STR) loci were collected from 130 unrelated Caucasians from North Bavaria using the AmpFlSTR Profiler multiplex system. The loci D3S1358, vWA, FGA, TH01, TPOX, CSF1PO, D5S818, D13S317, D7S820 and the sex test amelogenin were investigated. Allele frequencies, rates of heterozygosity and the discrimination power of the combined systems were calculated by statistical analysis. Except for D5S818 all loci met Hardy-Weinberg expectations. Received: 27 August 1998 / Received in revised form: 28 December 1998 |
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| Keywords: | Short tandem repeats (STRs) Multiplex PCR Laser fluorescence detection Population genetics |
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