| 低频电针降低神经病理痛大鼠背根神经节p-CREB的表达 |
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| 引用本文： | 张琪,谭颖颖. 低频电针降低神经病理痛大鼠背根神经节p-CREB的表达[J]. 河北中医药学报, 2011, 26(3): 36-37,2 |
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| 作者姓名： | 张琪 谭颖颖 |
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| 作者单位： | 陕西中医学院基础医学院,咸阳,712046 |
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| 基金项目： | 国家自然科学基金资助项目:No30700278、31171101;国家自然科学基金青年项目:NoP2X3;国家自然科学基金面上项目:No31171101 |
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| 摘 要： | 目的:观察低频脉冲电针对慢性神经病理痛大鼠背根神经节磷酸化环磷酸腺苷反应元件结合蛋白(p-CREB)表达的影响.方法:36只成年雄性SD大鼠,随机分为空白对照组、假手术组、模型对照组和电针治疗组,每组9只.模型对照组和电针治疗组采用右侧慢性坐骨神经结扎的方法,建立慢性神经病理痛模型.电针组大鼠给予低频电针刺激双侧"夹脊...
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| 关 键 词： | p-CREB 电针 足三里 夹脊穴 痛觉 镇痛 |
Low Frequency Electroacupuncture Decreasing p-CREB Expression in Dorsal Root Ganglia of Rats with Neuropathological Pain |
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| ZHANG Qi TAN Ying-ying College of Basic Medicine,Shaanxi TCM College. Low Frequency Electroacupuncture Decreasing p-CREB Expression in Dorsal Root Ganglia of Rats with Neuropathological Pain[J]. Journal of Hebei Traditional Chinese Medicine and Pharmacology, 2011, 26(3): 36-37,2 |
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| Authors: | ZHANG Qi TAN Ying-ying College of Basic Medicine Shaanxi TCM College |
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| Affiliation: | ZHANG Qi TAN Ying-ying College of Basic Medicine,Shaanxi TCM College(Xianyang 712046) |
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| Abstract: | Objective: to observe the effect of pulse electroacupuncture with low frequency on p-CREB expression in dorsal root ganglia of rats with chronic neuropathological pain.Methods: 36 SD rats were randomly divided into control group,sham operation group,model group and electroacupuncture group.Model group and electroacupuncture group were made by chronic sciatic nerve ligation on right side.The electroacupuncture group were given low frequency stimulation in bilateral Jiaji(EX-B 2) and Zusanli(ST 36) with wave ... |
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| Keywords: | p-CREB electroacupuncture Zusanli(ST 36) Jiaji(EX-B 2) algesia to relieve pain |
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