| 侧脑室内注射葛根素对大鼠血压和心率的影响 |
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| 引用本文： | 罗超,程德森,彭吉霞,何华琼. 侧脑室内注射葛根素对大鼠血压和心率的影响[J]. 大同医学专科学校学报, 2004, 24(2): 18-19 |
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| 作者姓名： | 罗超 程德森 彭吉霞 何华琼 |
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| 作者单位： | 郧阳医学院机能实验室，郧阳医学院，郧阳医学院，郧阳医学院 湖北十堰，442000 |
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| 摘 要： | 目的 :探讨侧脑室内注射葛根素降低大鼠动脉血压 (BP)和心率 (HR)的作用及机制。方法 :连续观察室内注射葛根素的大鼠 6 0minBP和HR变化曲线 ,并与对照组比较。结果 :给药后大鼠BP和HR明显降低 ,在 5min - 1 5min达最低值 ,与生理盐水对照组比较差异显著 (P <0 .0 1 )。结论 :侧脑室内注射葛根素有明显降低大鼠BP和HR作用。
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| 关 键 词： | 脑室内注射 葛裉素 大鼠 血压 心率 |
| 修稿时间： | 2004-01-20 |
The Effect of Intracenelro-ventricular Injection of PUERARIN on Arterial Blood Pressure and Heart rate in Rats |
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| Luo Chao Cheng Desen Peng Jixia et al. The Effect of Intracenelro-ventricular Injection of PUERARIN on Arterial Blood Pressure and Heart rate in Rats[J]. Journal of Datong Medical College, 2004, 24(2): 18-19 |
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| Authors: | Luo Chao Cheng Desen Peng Jixia et al |
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| Abstract: | Objective:To study the effect and mechanism of Intracenelro-ventricular Injection of PUERARIN on the reduction of arterial bood pressure(BP)and heart rate(HR) in rats.Methods:BP and HR acted as the index,to observe the effect of PUERARIN.injected on the artificially ventilaled SD rats,anesthsized with urethate and immobilized by gallamine triethiodide,with 60 minutes continual observation of changes of the curres of BP and HR.Then the result was compared with that of the contral group and NS group.Results:After injection of PUERARIN.The rats BP and HR dropped significantly,with the minimum level of BP and HR between 5 to 15 minutes. Compared with the control group and the NS group,BP and HR have marked difference (p<0.01).Conclusion:Intracenelro-ventricular Injection of PUERARIN has a significant effect on the reduction of rats BP and HR.. |
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| Keywords: | PUERARIN Arterial blood pressure Heart rate Intracerlbro-ventricular |
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