半乳糖凝集素-3与心血管疾病的研究进展

半乳糖凝集素-3（galectin-3,Gal-3）是凝集素家族成员之一，在不同的病理、生理过程中，发挥重要作用，包括免疫和炎性反应、糖尿病、肿瘤的增殖转移等。最近研究发现，半乳糖凝集素-3在心血管疾病发生、发展等方面有多种作用，其参与动脉粥样硬化的形成过程，诱导心肌纤维化和心室重构，参与心力衰竭发生，对心肌病的诊断也具有辅助意义，现就半乳糖凝集素-3在心血管疾病方面的相关研究进行综述。

Research progress of galectin-3 in cardiovascular diseases

Galectin-3 (Galectin-3, Gal-3) is one of the members of the lectin family and plays an important role in different Pathophysiology processes, including immune and inflammatory reaction, diabetes, tumor proliferation and metastasis. Recent studies have found that galectin-3 has a variety of roles in the development of cardiovascular diseases. it is involved in the formation of atherosclerosis and induced myocardial fibrosis and ventricular remodeling, involving in the occurrence of heart failure, it is helpful for the diagnosis of cardiomyopathy, Here is to make a review of research advances about galectin-3 in cardiovascular diseases.