多囊卵巢综合征的病因研究进展

多囊卵巢综合征是一种以雄激素过高的临床或生化表现、长期持续无排卵、卵巢多囊改变为主要特征的生殖功能障碍与代谢异常并存的内分泌紊乱综合征,其病因众多,发病机制复杂。近年来国内外逐渐将研究焦点转移至分子生物学方面,发现性激素、胰岛素相关、炎症因子、脂代谢相关等许多细胞因子在多囊卵巢综合征的发病过程中起到重要作用。本文就其最新病因研究进行综述并进行展望。

Progress in the Study of Etiology of Polycystic Ovary Syndrome

Polycystic ovary syndrome (PCOS) is a kind of endocrine syndrome with coexistence of reproductive dysfunction and metabolic abnormality characterized by high androgenic clinical or biochemical manifestations, long-term continuous anovulation, and polycystic ovarian change. The etiology and pathogenesis of polycystic ovary syndrome Mechanism complex. In recent years, the focus of research has been transferred to molecular biology, and many cytokines, such as sex hormones, insulin-related factors, inflammatory factors and lipid metabolism, play an important role in the pathogenesis of polycystic ovary syndrome. In this paper, the latest research on the etiology of the review and outlook.