Apoptotic retinal ganglion cell loss is accompanied by complement and cytokine response in the βB1-CTGF primary open-angle glaucoma mouse model |
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作者姓名: | Ana Maria Mueller-Buehl Sabrina Reinehr |
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作者单位: | Experimental Eye Research Institute |
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基金项目: | supported in part by FoRUM(RuhrUniversity Bochum,Germany,F903N-2017)Ernst and Berta Grimmke foundation(Germany);the Deutsche Forschungsgemeinschaft(Germany,RE-4543/1-1),all to SR。 |
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摘 要: | <正>Glaucoma is a multifactorial disease and occurs in many different species.In humans,glaucoma is accounted one of the leading causes for blindness worldwide.Due to glaucoma’s complexity,it is still unclear what pathomechanisms may be involved in its development in humans as well as in other species,such as canines.Diagnosis of glaucoma can be delayed because patients often do not notice a visual field loss until approximately30%of retinal ganglion cells (RGCs) are lost(Kerrigan-Baumrind ...
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关 键 词: | GLAUCOMA CYTOKINE |
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