早期血液滤过对重症胰腺炎的治疗效果及预后的研究

目的：探讨重症胰腺炎采用早期血液滤过治疗的临床价值。方法：通过前瞻性的随机对照方法的原则，纳入我院2011年9月至2015年11月收治的确诊为重症胰腺炎患者共100例，所有病例均在发病72小时内接受治疗，其中对照组采用的是常规对症内科治疗、胃肠减压、灌肠肠内营养、腹腔穿刺引流等方法；早期血液滤过治疗组则在对照组的基础上进行早期血液滤过治疗。分别观察两组患者1周内的APACHE-II和Balthazar CT评分，同时记录并发症发生率和病死率。结果：入院治疗后从第3天开始，早期血液滤过治疗组的APACHE-II评分低于对照组，两组差异具有统计学意义；入院后第7天行CT检查Balthazar评分早期血液滤过治疗组低于对照组，两组差异具有统计学意义；早期血液滤过治疗组7d后并发症和死亡的发生率低于对照组，差异具有统计学意义。结论：早期血液滤过治疗可以降低重症胰腺炎的并发症及病死率，是治疗重症胰腺炎有效方法之一。

Early hemofiltration treatment of severe acute pancreatitis and Prognosis

Objective: To investigate the use of severe acute pancreatitis early hemofiltration clinical value. Methods: Prospective randomized controlled method principles, incorporating our hospital from September 2011 to November 2015 admitted diagnosed with severe pancreatitis patients with a total 100 cases, all cases were treated within 72 hours of onset, wherein the control group It uses conventional symptomatic medical treatment, decompression, enema enteral nutrition, abdominal puncture drainage and other methods; early hemofiltration treatment group in the control group on the basis of early hemofiltration. Respectively, were observed within 1 week of the APACHE-II and Balthazar CT score, while recording morbidity and mortality. Results: After hospital treatment from the third day, early hemofiltration group APACHE-II scores than the control group, the difference was statistically significant; the first 7 days after admission CT was Balthazar score early hemofiltration group than the control group, the difference was statistically significant; early hemofiltration group 7d after the incidence of complications and death than the control group, a statistically significant difference. Conclusion: Early treatment can reduce blood filtration severe pancreatitis complications and mortality, is an effective method for the treatment of severe pancreatitis.