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Antiprotozoal activity of sesquiterpenes from jasonia glutinosa |
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| Authors: | Villaescusa-Castillo L Díaz-Lanza A M Gasquet M Delmas F Ollivier E Bernabé M Faure R Elias R Balansard G |
| Abstract: | Two sesquiterpene alcohols, 11 R]-eudesm-4(14)-en-5?,11,12-triol ( 1 ) and 11R]-eudesm-4(14)-en-5a,11-12-triol ( 2 ), from Jasonia glutinosa aerial parts (Asteraceae), have been tested using an in vitro technique against Leishmania donovani (promastigote forms) and Plasmodium falciparum . Sesquiterpene 1 was not effective at the assayed concentrations. Sesquiterpene 2 was found to be active against Leishmania donovani and Plasmodium falciparum . |
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