社区人群中外周动脉病与体质量指数相关性的研究

目的:分析上海嘉定社区人群中外周动脉病(PAD)的患病率及其与体质量指数(BMI)的关系。方法:采用整群抽样的方法,选取上海嘉定区40岁以上的社区居民5 435名。所有受试者均接受口服75 g葡萄糖耐量试验(OGTT)、血脂的测定以及踝肱指数(ABI)的检测。将ABI0.05)。BMI正常组、超重组及肥胖组的PAD患病率分别为6.67%、6.83%和12.62%,肥胖组PAD的患病率显著高于BMI正常组以及超重组(均P

The association between peripheral arterial disease and body mass index in a community-based population

Objective To investigate the association between the prevalence of peripheral arterial disease(PAD) and body mass index(BMI) in a middle aged and elderly community-based population.Methods With the cluster sampling method,5 435 residents(male: 2 001;female: 3 434) age 40 years or older were recruited in Jiading district,Shanghai between March to August in 2010.All participants undertook 75 g oral glucose tolerance test(OGTT),and had blood lipids and ankle-brachial index(ABI) measured.In this study,PAD was diagnosed by ABI<0.9 and participants were divided into three groups according to BMI value(normal: BMI<25.0;overweight: BMI between 25.0 to 29.9;obesity: BMI≥30.0).Logistic regression analysis was performed to analyze the association between BMI and prevalence of PAD Results In this community-based population study,the prevalence of PAD was 7.10%,and were 8.35% and 6.38% in male and female,respectively(P<0.05).The prevalences of PAD were 6.67%,6.83% and 12.62% in those who had normal BMI,overweight and obesity,respectively(all P<0.05).After adjusting confounders,logistic regression analysis revealed that BMI was positively related with the prevalence of PAD.Those who was obesity had an increase of 92% in risk of having PAD when compared with those having normal BMI(OR=1.92,95%CI:1.32-2.75;P=0.000 5).Conclusions The prevalence of PAD increased up to 7.10% in this community-based population in Jiading district,Shanghai.Obesity was an independent risk factor for PAD.