502例非淋菌性尿道炎中衣原体、支原体感染的检测与耐药性分析

目的了解非淋菌性尿道炎（NGU）中衣原体、支原体感染的情况及耐药性。方法对502例NGU患者的分泌物、前列腺液等进行衣原体、支原体培养、鉴定、计数及药敏试验。结果502例中衣原体或支原体阳性者232例，总阳性率46．2％；衣原体（Ct）阳性27例，解脲脲原体（Uu）阳性221例，感染率分别为5．3％、44．0％；混合感染的阳性率为3．1％（16例）；支原体对12种抗菌药物敏感性最高的是米诺环素和多西环素（97．3％o、97．3％）；耐药性较高的为氧氟沙星（72．3％）、环丙沙星（55．2％）。结论NGU患者支原体感染率高，以Uu感染为主；且对氧氟沙星、环丙沙星等药物的耐药性呈上升趋势，并出现多药耐药性；因此，对NGU患者，加强支原体培养和药敏试验，对指导临床用药，最大限度地控制耐药菌株的产生，尤为重要。

Detection and drug resistance of chlamydia and mycoplasma strains from non-gonococcus urethritis patients

Objective To investigate chlamydozoan and mycoplasma in urogenital tract infection and their resistance against antibiotics in suspected non-gonococcus urethritis (NGU) patients. Methods Chlamydozoan antigen was qualitatively determined by using immunochromatography technique. Mycoplasma culture and drug sensitivity test were carried out with mycoplasma drug sensitivity kit,and the sensitivity of 12 kinds of antibiotics to mycoplasma was analyzed. Results Among the 502 patients suspected with NGU,232 were p...