| 老年高血压患者颈动脉粥样硬化与胰岛素抵抗相关性研究 |
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| 引用本文： | 张曦元,梁伟东,赵献明,赵扬.老年高血压患者颈动脉粥样硬化与胰岛素抵抗相关性研究[J].广西医学,2010,32(1):31-34. |
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| 作者姓名： | 张曦元 梁伟东 赵献明 赵扬 |
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| 作者单位： | 广西南宁市第一人民医院,南宁市,530022 |
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| 摘 要： | 目的观察老年高血压患者颈动脉粥样硬化的特点,探讨胰岛素抵抗与老年高血压病动脉粥样硬化的相关性。方法单纯高血压组（EH）组98例,高血压合并糖尿病组（EH＋DM组）103例,健康对照组92例,均行超声检查颈动脉内膜中层厚度（IMT）,测定空腹血糖和胰岛素、动态血压、甘油三酯、胆固醇、高密度脂蛋白、BMI,计算稳态模式评估法的胰岛素抵抗指数（HOMA-IR）,并与心血管危险因素做相关分析。结果IMT与HOMA-IR、BMI和空腹血糖呈正相关;IMT、FBG、血脂、BMI等指标,EH＋DM组显著高于EH组（P〈0.05）,EH组高于对照组（P〈0.05）。结论老年高血压合并糖尿病患者IMT显著增高,糖尿病合并高血压可加速动脉粥样硬化的进展,而且与高血压患者胰岛素抵抗的发生、发展密切相关。
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| 关 键 词： | 高血压 糖尿病 胰岛素抵抗 颈动脉内膜中层厚度 |
Relationship between Carotid Atherosclerosis and Insulin Resistance in Elderly Hypertensive Patients |
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| ZHANG Xi-yuan,LIANG Wei-dong,ZHAO Xian-ming,ZHAO Yang.Relationship between Carotid Atherosclerosis and Insulin Resistance in Elderly Hypertensive Patients[J].Guangxi Medical Journal,2010,32(1):31-34. |
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| Authors: | ZHANG Xi-yuan LIANG Wei-dong ZHAO Xian-ming ZHAO Yang |
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| Institution: | The First People's Hospital of Nanning;Nanning 530022;China |
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| Abstract: | Objective To observe the characteristics in elderly hypertensive patients with carotid atherosclerosis,and the relationship between insulin resistance in elderly patients with hypertension and atherosclerosis.Methods 293 patients were divided into 3 groups:simple hypertension(EH)group with 98 cases;hypertension with diabetes mellitus(EH & DM)group was 103 cases;and the control group which was 92 cases of normal blood pressure.All patients underwent carotid ultrasound intima-media thickness(IMT)test.Determin... |
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| Keywords: | Hypertension Diabetes mellitus Insulin resistance Carotid artery intima-media thickness |
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