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Immunophilins: their properties and their potential role in therapeutic drug monitoring
Authors:Soldin S J
Affiliation:Department of Laboratory Medicine, Children's National Medical Center, Washington, DC 20010, USA.
Abstract:This article reviews recent developments in the immunophilin arena and the current state of knowledge about the biochemical properties of immunophilins. The role of immunophilin-binding assays is also explored with the conclusion that some of these immunosuppressive-drug-binding proteins may provide better assays for sirolimus and tacrolimus than current immunoassays.
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