ICU肺部感染的病原学以及药敏分析

目的 探讨我院ICU肺部感染的病原学特征及其药敏.方法 分析我科近年来收治的124例肺部感染患者的临床资料,并对其病原学特征以及相关药敏试验结果进行分析.结果 我科重症患者肺部感染主要致病菌以革兰阴性菌居多,主要包括铜绿假单胞菌、金黄色葡萄球菌、白色链球菌、克雷伯杆菌、肺炎链球菌等,其中革兰阴性菌较头孢噻肟、头孢哌酮/舒巴坦等敏感,革兰阳性球菌病原菌对万古霉素等较为敏感.结论 ICU肺部感染患者的病原菌种类多样,以革兰阴性菌为主,监测重点为多重耐药菌株,结合药敏试验合理选择抗生素是关键.

Etiology and drug sensitivity analysis of pulmonary infection in ICU

Objective To investigate the etiology of lung infection in ICU and its drug sensitivity. Methods The clinical data of 124 patients with lung infection were retrospectively analyzed to summarize its etiological characteristics and drug sensitivity. Results The major pathogenic bacteria of lung infection in ICU were gram-negative bacteria, which included pseudomonas aeruginosa, staphylococcus aureus, white streptococcus, klebsiella, and streptococcus pneumoniae. Gram negative bacteria were sensitive to cefotaxime and cefopera- zane/sulbactam, and gram-positive bacteria were sensitive to vancomycin. Conclusion The pathogenic bacteria of lung infection in ICU are various, which mainly are gram-negative bacteria. Most of them showed a multi-drug resistance, and the use of antibiotics should be strictly based on the results of drug sensitivity test.