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β-环糊精包合干姜提取物的方法比较
引用本文:傅秀娟,何兵,刘艳. β-环糊精包合干姜提取物的方法比较[J]. 泸州医学院学报, 2011, 34(2): 127-129
作者姓名:傅秀娟  何兵  刘艳
作者单位:泸州医学院药学院药剂学教研室,四川,泸州,646000
摘    要:目的:制备干姜提取物的β-环糊精包合物,增加其稳定性。方法:分别采用研磨法、超声法及饱和水溶液法对干姜提取物进行包合,以HPLC法测定其中6-姜辣素含量,以包合物得率和包合率加权评分为指标,确定最佳包合方法。结果:以研磨法制备的包合物得分最高。结论:研磨法包合干姜醇提物的效果最佳。

关 键 词:β-环糊精  包合  研磨法  超声法  饱和水溶液法

COMPARISON OF DIFFERENT METHODS FOR ZINGIBER OFFICINALE ROSC.EXTRACT INCLUSION
Fu Xiujuan,et al. COMPARISON OF DIFFERENT METHODS FOR ZINGIBER OFFICINALE ROSC.EXTRACT INCLUSION[J]. Journal of Luzhou Medical College, 2011, 34(2): 127-129
Authors:Fu Xiujuan  et al
Affiliation:Fu Xiujuan,et al Department of phamceutical Andlysis,School of Pharmacy,Luzhou Medical College
Abstract:Objective:To prepare β-cyclodextrin inclusion complex of Zingiber officinale Rosc.extract,in order to enhance its stability.Methods:Grounding method,ultrasonic method and saturated aqueous solution method were investigated.The content of 6-gingerol was determined by HPLC,and with the weighted grading of inclusion rate and yield rate as the index,the optimum method was defined.Results:Grounding method scores highest.Conclusion:Grounding method is the optimum method for Zingiber officinale Rosc.ethanol extract.
Keywords:β-cyclodextrin  Inclusion  Grounding method  Ultrasonic method  Saturated aqueous solution method
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