口腔念珠菌病8例临床病理分析

目的:探讨口腔念珠菌病的临床诊断与病理诊断,以减少误诊.方法:对8例病理诊断为口腔念珠菌病的患者的临床资料进行回顾性分析,并对其标本进行组织病理学HE和PAS染色研究.结果:8例患者病理诊断为口腔念珠菌病,而临床上均未考虑为本病.常规组织病理切片均见上皮内微小脓肿,PAS染色可见真菌菌丝侵入上皮表层.结论:临床上遇到长期不愈的增生或溃疡型病变时,应考虑是否有念珠菌感染;组织病理学检查发现病变上皮内出现微小脓肿时,应高度怀疑本病,PAS染色有助于确诊.

Clinical and pathological analysis of 8 patients with oral candidiasis

PURPOSE: To investigate the clinical and pathological diagnosis of oral candidiasis and reduce misdiagnosis. METHODS: The medical records of 8 patients with oral candidiasis were reviewed retrospectively, HE and PAS staining of histopathology were applied to study the specimens. RESULTS: It was found that oral candidiasis were identified by pathological diagnosis, but weren't considered clinically. Minor abscesses were all detected in the epithelium of conventional histopathologic sections, the hyphae were shown by PAS staining invading the epithelium. CONCLUSIONS: The results suggest that candidal infections should be considered, if there are hyperplastic or ulcerative lesions which last for long time; when minor abscesses are detected in the epithelium by histopathologic examination, oral candidiasis should be highly suspected, and be confirmed by PAS staining.