黄色肉芽肿性肾盂肾炎病理探讨（附2例报告）

黄色肉芽肿性肾盂肾炎是一种罕见的慢性炎性疾患，本文报告２例。临床表现为一侧胁肋部痛，消瘦、体重减轻、发热和患肾功能受损。静脉肾盂造影、Ｂ型超声有时显示占位病变。病理上为黄色肉芽肿形成，显微镜下病灶内见大量泡沫细胞及炎细胞浸润。手术前确诊甚为困难，应结合临床资料、尿培养、尿细胞学、肾穿刺活检，Ｘ线及Ｂ型超声等检查做出诊断。手术切除后不复发。其发病可能与感染、梗阻及脂代谢异常有关。该病应与肾肿瘤等疾病鉴别诊断

Xanthogranumatous pyelonephritis

Xanthogranulomatous pyelonephritis is a rare chronic inflammatory disease,two cases are reported.Clinically,unilateral flank pain,fever,emaciation,weight loss and impairment of renal function.IVP,B-ultrasound showed space occupying lesion.Pathologically,xanthogranumatous lesion was formed.Microscopically,lesion areas are composed of large uniform lipidladan macrophages(foam cells) and inflammatory cells infiltration.Preopertive diagnosis is very difficult.In order to get an accurate diagnosis,we must combine clinical data with urinary cytology,urine cultures,fine needle aspiration biopsy,IVP and B-ultrasound diagnosis.It has never recurred after nephrectomy.Its etiopathogensis may related with infection,obstruction,and abnormality in the lipid metabolism.It should be differential diagnosis with tumor and other diseases.