实验性瘘管刺激前庭诱发电位的研究

目的：探讨前庭诱发电位研究的简便有效的前庭刺激方式。方法：对１２只豚鼠行右上半规管壶腹部骨壁开窗造瘘,采用特殊设计的瘘管刺激探我装置机械刺激膜腹壁,得到一组由３－４个正波为主要成分的诱发电位。结果：该是位波形清晰,重复性较好,其Ｐ１－Ｐ４各波的潜伏期,波宽和振幅等值均较稳定,豚鼠死亡,该波消失;颈髓横断、眶内容物及面神经切除均不影响电位。庆大霉素致内耳严重损害,该波消失;行上半规管壶腹部破坏,上半

Research of experimental fistula stimuli vestibule evoked response

Objective: To investiqate a way of stimulation for experimental vestibul evoked response. The artificial fistula of right upper semicircular canal was made in 12 guineapig. Method: Using a fistula stimuli probe device designed specially. Result: We obtain a potential consisting of 3-4 positive waveforms. We called it the fistula stimuli vestibule evoked response (FsVeR). They had a coincide character. The response disappeared when the animal died. The cervical spinal section, orbital removal and facial nerve removal had little effects to FsVeR. When severe inner ear damage produced by Gentamycin injection, the potential disappeared. The potential disappeared but ABR were existed. When the upper semicircular canal and its nerve damage. The noise screen had a little affection to FsVeR. Conclusion: These results indicated that FsVeR was mainly originated from the vestivbule system. The development of this recording technique provides a new method and maybe has important value for vestibule experimental research work.