健康呼吸中心对支气管哮喘患者管理和生活质量的影响

目的 评价健康呼吸中心管理与系统教育模式对哮喘防治及哮喘患者生活质量的影响.方法 对2005年9月至今就诊"健康呼吸中心",参加过"哮喘之家"活动的642名接受规范化治疗疗程3年以上的慢性持续哮喘患者,随机分为严格管理(依从性好)和松懈管理(依从性不好)两组,由哮喘专科门诊医生以面对面问卷方式调查门诊成年哮喘患者对疾病...

Clinical center-based health management and quality of life of patients with asthma

Objective To evaluate the effects of clinical center-based health management on quality of life （QOL） of patients with asthma. Methods A total of 642 patients who had received standard antiasthma treatment over 3 years in our clinical center from September 2005 up to now were randomly assigned to the good compliance group （group A, n = 326）and bad compliance group （group B, n = 316）. A questionnaire was used to estimate the awareness about asthma, medical therapy and disease control. Levels of QOL were compared at 6 months and 1 and 3 years after health education. Results In group A, uncontrolled,partly controlled, and completely controlled asthma were found in 21%, 47%, and 32% participants, respectively. Significant difference of QOL was shown between the 2 groups after the intervention （P 〈 O. 05）. At 6 months, forced expiratory volume in one second （ FEV1 ）, percentage of predicted FEV1 （FEV1% pre）, and peak expiratory flow rate （PEF）were significantly improved in group A （all P 〈 0. 05 ）, although acute attack and hospitalization were largely reduced. In comparison with baseline,6 months and 1 year, self-reported QOL, limitation of motion, stimulus avoidance and response, and disease concerns were significantly changed at 3 years. Conclusions Clinic center-based health management could benefit disease control and QOL of patients with asthma.