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A simple method for the evaluation of antiseptic and disinfectant virucidal activity
Authors:M Boudouma  L Enjalbert  J Didier
Affiliation:Laboratoire de Bactériologie- Virologie, Faculté de Médecine Rangueil, Bât. LI - Chemin du Vallon, F-31054 Toulouse Cedex, France
Abstract:A simple method for evaluating the virucidal activity of water-soluble antiseptic and disinfectant products using poliovirus type 1 (Sabin strain) is described. Using a commercial concentrator, kinetic studies of four products were carried out. It was shown that 2% glutaraldehyde and 5% povidone iodine are rapidly virucidal. 0.2% glutaraldehyde and 2.5% noxythiolin (37 degrees C) are considerably less effective. 0.05% chlorhexidine digluconate has no virucidal activity.
Keywords:antiseptic  disinfectant  poliovirus  virucidal activity  dilution ultrafiltration
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