| 拟除虫菊酯类农药对大鼠肝线粒体、微粒体Ca~（2＋）－ATP酶活力的影响 |
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| 引用本文： | 张秀莲,夹访贤,于丽华. 拟除虫菊酯类农药对大鼠肝线粒体、微粒体Ca~（2＋）－ATP酶活力的影响[J]. 中国公共卫生学报, 1994, 0(5) |
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| 作者姓名： | 张秀莲 夹访贤 于丽华 |
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| 作者单位： | 山东医科大学毒理学研究室 |
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| 摘 要： | 采用离体实验方法，观察了拟除虫菊酯类农药溴氰菊酯、氯氰菊酯对大鼠肝线粒体、微粒体Ｃａ２＋－ＡＴＰ酶活力的影响。结果表明，加入溴氰菊酯、氯氰菊酯１５ｍｉｎ后，各剂量组线粒体、微粒体Ｃａ２＋ＡＴＰ酶均有明显的抑制作用，与对照组相比均具有显著性差异，（Ｐ＜０．０５或Ｐ＜０．０１），且存在明显的剂量－效应关系。作用３０ｍｉｎ后各剂量组线粒体、微粒体Ｃａ２＋－ＡＴＰ酶仍继续下降，未见有恢复的趋势。
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| 关 键 词： | 溴氰菊酯，氯氰菊酯，线粒体，微粒体，Ca~（2＋）－ATP酶 |
Effect of Decamethrin and Cypermethrin on Activities of Ca-ATPase of Mitochondria and Microsome of Rat Liver |
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| Zhang Xiulian,et al.. Effect of Decamethrin and Cypermethrin on Activities of Ca-ATPase of Mitochondria and Microsome of Rat Liver[J]. , 1994, 0(5) |
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| Authors: | Zhang Xiulian et al. |
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| Affiliation: | Jinan 250012 |
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| Abstract: | In this paper we observed the effect of Decamethrin and Cypermethrin on the activities of Ca-ATPase of mitochndria and microsome of rat liver in vitro. The result indicated that Decamethrin and Cypermethrin could inhibit the activities of Ca-ATPase often incubating for 15 minutes. There was doseeffect relation, P< 0. 05 or 0. 01. compared with control group. The activities of Ca-ATPase still decreased after incubating for 30 minutes. |
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| Keywords: | Decamethrin Cypermethrin Mitochondria Micrusome Ca-ATPase |
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