Affiliation: | (1) Dept. of Microbiology, All India Institute of Medical Sciences (A.I.I.M.S.) , Ansari Nagar, New Delhi-110029, India;(2) Dept. of Medicine, All India Institute of Medical Sciences, New Delhi, India |
Abstract: | Abstract. Background: As the number of AIDS cases increases in India,information available among clinicians about the prevalence ofopportunistic infections (OIs) is scarce. The aim of the presentstudy was to document the characteristic OIs of HIV-infectedNorth Indian patients along with theirCD4+ counts. Patients andMethods: The study group consisted of subjects with confirmedserodiagnosis of HIV, attending the medical clinics at atertiary health care center in North India. TheCD4+ counts were estimated by FACSCalibur (BD) flow cytometer. Simultaneously, routinemicrobiology smears, cultures and serology were performed toconfirm OI. Results: In this retrospective study of 421 subjects, thepredominant OI was tuberculosis (47%, 189 cells/µl), followed byparasitic diarrhea (43.5%, 227 cells/µl) and oral candidiasis(25.2%, 189 cells/µl). Conclusion: Tuberculosis was the most frequent OI in the HIV-infectedpatients studied, and the major mode of transmission of HIV wasby sexual route. The median CD4+counts observed were lower when compared to otherstudies. |