The effect of Paeonol on erythrocyte deformability determined by micropipette aspiration technique] |
| |
Authors: | W Li S Cai Y Wang Q Huang G Song |
| |
Institution: | Guangzhou University of Traditional Chinese Medicine, Guangzhou 510405. |
| |
Abstract: | OBJECTIVE: The effect of Paeonol (PAE) on erythorcyet(RBC) deformability was studied in order to provide experimental data for the application in clinic and the evaluation in pharmacological action. METHODS: Micropipette Aspiration Technique was used to determine the RBC deformation length. The method of calculation was also simplified and a new apparent deformation Index(ADI) was defined. RESULTS: PAE could increase the ADImin and ADImax and decrease Tmax significantly. CONCLUSION: PAE has the effect of deformational ability on RBC. Micropipette aspiration technique is a feasible method for determining the effect of traditional Chinese medicine on erythrocyte deformability. |
| |
Keywords: | |
|