| 菝葜中黄酮和二苯乙烯类成分的研究 |
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| 引用本文： | 邵波,郭洪祝,果德安. 菝葜中黄酮和二苯乙烯类成分的研究[J]. 中草药, 2009, 40(11): 1700-1703 |
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| 作者姓名： | 邵波 郭洪祝 果德安 |
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| 作者单位： | 1. 北京大学药学院,北京,100083
2. 北京市药品检验所,北京,100035 |
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| 基金项目： | ,国家杰出青年科学基金, |
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| 摘 要： | 目的 研究菝葜Smilax china的化学成分.方法 采用硅胶、Sephadex LH-20、ODS柱色谱及半制备液相色谱等技术分离菝葜的化学成分,根据化合物的理化性质及波谱数据鉴定化合物的结构.结果 从菝葜中分离得到11个化合物,其中黄酮类成分7个:二氢山柰酚-5-O-β-D-葡萄糖苷(Ⅰ)、黄杞苷(Ⅱ)、异黄杞苷(Ⅲ)、双氢槲皮素-3'-O-葡萄糖苷(Ⅳ)、3,5,7,3',5'-五羟基二氢黄酮醇(Ⅴ)、落新妇苷(Ⅵ)和槲皮素-3'-O-葡萄糖苷(Ⅶ);二苯乙烯类化合物4个:白藜芦醇苷(Ⅷ)、蔗草素A(scirpusin A,Ⅸ)、白藜芦醇(Ⅹ)和2,4,3',5'-四羟基芪(Ⅺ).结论 化合物Ⅳ～Ⅸ均为首次从该植物中分离得到;化合物Ⅸ的碳谱数据为首次报道.
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| 关 键 词： | 菝葜 黄酮类 二苯乙烯类 |
| 收稿时间： | 2009-03-19 |
Flavonoids and stilbenes from Smilax china |
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| Shao Bo,Guo Hongzhu and Guo Dean. Flavonoids and stilbenes from Smilax china[J]. Chinese Traditional and Herbal Drugs, 2009, 40(11): 1700-1703 |
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| Authors: | Shao Bo Guo Hongzhu Guo Dean |
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| Affiliation: | School of Pharmaceutical Sciences,Peking University,Beijing 100083,China;Beijing Institute for Drug Control,Beijing 100035,China;School of Pharmaceutical Sciences,Peking University,Beijing 100083,China |
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| Abstract: | Objective To study the chemical constituents of Smilax china.Methods The compounds were isolated by silica gel,Sephadex LH-20,ODS chromatography,and semi-preparative HPLC.Their structures were elucidated on the basis of MS and NMR spectroscopic analyses.Results Seven flavonoids and four stilbenes were isolated and identified as dihydrokaempferol-5-O-β-D-glucoside(Ⅰ),engeletin (Ⅱ),isoengeletin (Ⅲ),dihydroquercetin-3-O-glycoside(Ⅳ),3,5,7,3',5'-pentahydroxy-flavanonol (Ⅴ),astilbin (Ⅵ),quercetin-3'-O-glycoside(Ⅶ),piceid(Ⅷ),scirpusin A (Ⅸ),resveratrol (Ⅹ),and oxyresveratrol (Ⅺ).Conclusion Compounds Ⅳ-Ⅸ are isolated from this plant for the first time,among which the ~(13)C-NMR data of compound Ⅸ is reported firstly. |
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| Keywords: | Smilax china L flavonoids stilbenes |
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