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多裂委陵菜化学成分的研究
引用本文:薛培凤,乔梁,梁鸿,赵玉英. 多裂委陵菜化学成分的研究[J]. 北京大学学报(医学版), 2004, 36(1): 21-23
作者姓名:薛培凤  乔梁  梁鸿  赵玉英
作者单位:北京大学药学院天然药物化学研究室,北京,100083;北京大学药学院天然药物化学研究室,北京,100083;北京大学药学院天然药物化学研究室,北京,100083;北京大学药学院天然药物化学研究室,北京,100083
摘    要:目的:研究多裂委陵菜(Potentilla multifida L.)的化学成分. 方法:用色谱法和波谱法对多裂委陵菜的化学成分进行分离和结构鉴定. 结果:分离、鉴定了5个化合物:3β,24-二羟基-乌苏-12-烯(1);3β-羟基-乌苏-12-烯-28-酸(2);2α,3α,19α-三羟基-乌苏-12-烯-28-酸(3);2α,3β,19α-三羟基-乌苏-12-烯-28-酸(4);3β,24-二羟基-齐墩果-12-烯-28-酸(5). 结论:5个化合物均为首次从该种植物获得,1和5为首次从该属植物获得,1为新天然产物.

关 键 词:委陵菜属  三萜类  色谱法
文章编号:1671-167X(2004)01-0021-03
修稿时间:2003-08-13

Studies on the chemical constituents from Potentilla multifida L.
Pei-Feng Xue,Liang Qiao,Hong Liang,Yu-Ying Zhao. Studies on the chemical constituents from Potentilla multifida L.[J]. Journal of Peking University. Health sciences, 2004, 36(1): 21-23
Authors:Pei-Feng Xue  Liang Qiao  Hong Liang  Yu-Ying Zhao
Affiliation:Department of Natural Medicines, Peking University School of Pharmceutical Sciences, Beijing 100083, China.
Abstract:OBJECTIVE: To study the chemical constituents of Potentilla multifida L. METHODS: Chemical constituents were isolated by the repeated silica gel chromatography and Sephadex LH-20, and their structures were identified by the spectral analysis. RESULTS: Five compounds were obtained as follows: 3beta,24-dihydroxyl-urs-12-ene (1), ursolic acid (2), euscaphic acid (3), tormentic acid (4), and epihedaragenin (5). CONCLUSION: Five compounds were isolated from this plant for the first time. Compounds 1 and 5 were isolated from this genus for the first time. Compound 1 was a new natural product.
Keywords:Potentilla  Triterpenes  Chromatography
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