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实验性肺动脉高压及其治疗泡内动脉病变的图像形态定量分析
引用本文:王柏苓,崔松山,杨白玉,周成双,丁万群,孙本韬,王璞,于雪梅,林平,张岩. 实验性肺动脉高压及其治疗泡内动脉病变的图像形态定量分析[J]. 中国医学科学院学报, 1996, 0(2)
作者姓名:王柏苓  崔松山  杨白玉  周成双  丁万群  孙本韬  王璞  于雪梅  林平  张岩
作者单位:哈尔滨医科大学,山西医学院
摘    要:应用图像分析仪测量了35只实验性肺动脉高压及其经治疗的大鼠泡内动脉的管腔面积/管总面积(EA/TA)、管壁面积/管总面积(WA/TA)及管壁厚/管外径(WD/TD)3个相对比值。结果发现,高压组较对照组及中药单体治疗组大鼠EA/TA值均显著减少,而WA/TA及WD/TD值均显著增大。这对肺动脉高压及其经治疗的病理形态定量研究、诊断及推测疾病预后具有一定的实用意义。

关 键 词:肺动脉高压,泡内动脉,图像形态定量分析

Image Morphological Quantitative Analysis of Pathological Changes of Intra-acinarArteries in Experimental Pulmonary Artery Hypertension and Outcomes of Treatment
Wang Bailing,Chui Songshan, Yang Baiyu,Zhou Chengshuang Ding Wanqun,et al. Image Morphological Quantitative Analysis of Pathological Changes of Intra-acinarArteries in Experimental Pulmonary Artery Hypertension and Outcomes of Treatment[J]. Acta Academiae Medicinae Sinicae, 1996, 0(2)
Authors:Wang Bailing  Chui Songshan   Yang Baiyu  Zhou Chengshuang Ding Wanqun  et al
Abstract:The relative ratios of vessel lumen area/total area(EA/TA),vessel wall area /total area(MA/TA) and vessel wall thickness/vessel external diameter(WD/TD)of intra-acinar ar-teries were studied with image analysor in 35 rats of experimental pulmonary artery hyper-tension and outcomes of treatment.All the rats were divided into control group(R0), hy-pertension group(R1)and treated groups (R2),(R3) and(R4).The results showed rela-tive ratios of EA/TA decreased significantly in the palmonary artery hypertension group incomparison with the control and treated groups, while the values of WA/TA and WD/TDincreased significantly,The results may be valuable for morphological quantitative study,di-agnosis of pulmonary artery hypertension and prediction of the disease prognosis.
Keywords:pulmonary artery hypertension  intra-acinar artery  image morphological quantitative analy-sis  
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