Department of Neurology, Athens University, Eginition Hospital, Athens, Greece;1st Department of Medicine, Athens University, Laikon General Hospital, Athens, Greece
Abstract:
A Greek family is presented in which seven members suffered from benign hereditary chorea (a rare autosomal dominant non-progressive chorea without dementia). All patients and three informative healthy relatives were submitted to DNA analysis using probes from loci linked to Huntington's disease. The results confirm one previous suggestion that these two disorders are not allelic and that they should be considered as two distinct genetic entities.