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多指标综合水平正交设计优选连钱草提取工艺的实验研究
引用本文:葛少祥,彭代银,刘金旗. 多指标综合水平正交设计优选连钱草提取工艺的实验研究[J]. 安徽医药, 2007, 11(6): 490-491
作者姓名:葛少祥  彭代银  刘金旗
作者单位:安徽中医学院药学院、安徽省高等学校省级现代中药重点实验室,安徽合肥,230038;安徽中医学院药学院、安徽省高等学校省级现代中药重点实验室,安徽合肥,230038;安徽中医学院药学院、安徽省高等学校省级现代中药重点实验室,安徽合肥,230038
摘    要:目的 建立最佳的连钱草脂溶性提取物提取工艺.方法 设计合理的提取工艺流程对连钱草进行提取.采用UV法测定提取物中甾醇的含量.采用综合水平的正交表,以脂溶性提取物、甾醇含量和出膏率的综合评分为指标,对实验结果进行极差和方差分析.结果 连钱草的最佳提取条件为95%乙醇、6倍量、提取2次,每次提取1 h.结论 通过对实验结果的极差、方差分析,确定了适宜于工业生产的最佳提取工艺.

关 键 词:连钱草  正交试验  提取物  甾醇
修稿时间:2007-03-26

To select the optimal extraction technique for glechomae by employing the method of orthogonal trial with mixed levels and composite index
GE Shao-xiang,PENG Dai-yin,LIU Jin-qi. To select the optimal extraction technique for glechomae by employing the method of orthogonal trial with mixed levels and composite index[J]. Anhui Medical and Pharmaceutical Journal, 2007, 11(6): 490-491
Authors:GE Shao-xiang  PENG Dai-yin  LIU Jin-qi
Affiliation:Anhui Key Laboratory of Modernized Chinese Material Medicine, Anhui College of TCM, Hefei 230038
Abstract:Aim To work out the optimal lipid soluble extraction technique for the Glechomae longituba.Methods A reasonable extraction technological process of extract was designed.UV method was adopted to quantitatively determine the sterol in the extraction.The method of orthogonal trial was employed with mixed levels and composite index and theprocessing was detected with range analysis and variance analysis.Results The optimal extraction technique for glechoma:using 95% alcohol,6 times of herbal medicine's weight to extract the herb for two times and one hour per time.Conclusion The optimal technique applicable to industrial production was obtained.
Keywords:glechomae   orthogonal trial    extract   sterol
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