百普力肠内营养对结直肠疾病术后患者吻合口瘘风险的影响

目的：观察结直肠疾病术后应用新型肠内营养剂百普力的临床效果及不良反应。方法将结直肠手术患者64例随机分为治疗组和对照组，各32例。对照组经外周静脉给予肠外营养，治疗组经鼻肠管给予肠内营养，治疗周期均为7 d。观察两组患者术后体重、营养状况、肠道功能恢复情况、并发症和不良反应，记录平均住院时间。结果治疗组患者体重、外周血淋巴细胞、血白蛋白、血浆前白蛋白均显著高于对照组（ P ﹤0.05），肛门排气时间、排便时间、平均住院时间均较对照组显著缩短（ P ﹤0.05），肠黏膜损伤发生率较对照组显著降低（ P ﹤0.05），且并未增加吻合口瘘风险。结论结直肠疾病术后早期肠内营养能有效改善患者术后营养不良状态，减少肠黏膜损害，促进肠道功能恢复，缩短住院时间，并不会增加吻合口瘘的风险。

Influence of New Type Enteral Nutrition Agent Baipuli Applied in Patients with Colorectal Surgery on Anastomotic Fistula Risk

Objective To observe the efficacy and adverse reactions of new type enteral nutrition agent Baipuli applied in the patients of colorectal surgery. Methods 64 cases of colorectal surgery were randomly divided into the treatment group and the control group, 32 cases in each group. Parenteral nutrition was given via peripheral vein for 7 d in the control group. Enteral nutrition was given via nasointestinal tube for 7 d in the treatment group. The postoperative body weight, nutrition status, recovery situation of the intestinal function, complications and adverse reactions were observed in the two groups, and the average hospitalization time was recorded. Results The body weight, peripheral blood lymphocytes, blood albumin and plasma prealbumin in the treatment group were significantly higher than those in the control group（ P ﹤ 0. 05）, the anus exhaust time, defecation time and average hospital stay in the treatment group were significantly shortened compared with the control group （ P ﹤ 0. 05 ） , the occurrence rate of intesinal mucosal injury in the treatment group was decreased significantly compared with the control group（ P ﹤ 0. 05） moreover without increasing the anastomotic fistula risk. Conclusion Early enteral nutrition in the patients of colorectal surgery can effectively improve the postoperative cacotrophy status, reduce intesinal mucosal injury, promote the recovery of intestinal function and shorten the hospitalization time without increasing the risk of anastomotic fistula.