SO-CALLED "PAPILLARY and CYSTIC NEOPLASM OF THE PANCREAS" |
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| Authors: | Terumi Kamisawa Masashi Fukayama Morio Koike Ikuo Tabata Atsutake Okamoto |
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| Affiliation: | Department of Pathology, Tokyo Metropolitan Komagome Hospital, Tokyo;*Department of Internal Medicine, Tokyo Metropolitan Komagome Hospital, Tokyo;**Department of Surgery, Tokyo Metropolitan Komagome Hospital, Tokyo |
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| Abstract: | A case of so-called "papillary and cystic neoplasm of the pancreas" (PCNP) was reported and investigated immunohistochemically and ultrastructurally. A tumor of the pancreatic head in a 21-year-old female was curatively resected. The tumor was cystic and histologically consisted of uniform cells in papillary and solid structure. Although there was no immunoreactivity for pancreatico-gut hormones or secretory products of the pancreas in the tumor cells, most of the tumor cells were diffusely immunoreactive for neuron-specific enolase (NSE). Some neurosecretory granules were detected in the tumor cells ultrastructurally. Both facts suggested endocrine cell character of the tumor. Certain cases of PCNP might show a differentiation to endocrine cells. |
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