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COMPASS PLOTS: A COMBINATION OF STAR PLOT AND ANALYSIS OF MEANS TO VISUALIZE SIGNIFICANT INTERACTIONS IN COMPLEX TOXICOLOGY STUDIES
Authors:Kamon Budsaba  Charles E Smith  Jim E Riviere
Institution:1. Department of Statistics, North Carolina State University Raleigh, North Carolina, USAkbudsab@stat.ncsu.edu;3. Department of Statistics, North Carolina State University Raleigh, North Carolina, USA;4. Center for Cutaneous Toxicology and Residue Pharmacology, North Carolina State University, Raleigh, North Carolina, USA
Abstract:The Compass Plot, a new graphical methodthat combines the advantages of the star plot andthe analysis of means (ANOM), has beenintroducedfordisplaying the results of experiments. Incontrast to the star plot, this plot allows statistical inferences to be made for treatment and for factor effects. In contrast to ANOM, this plot is good for comparison in multiresponse experiments, a scenario becoming more commonplace in toxicology with the advent of increasing numbers of chemical mixture studies. An example of a 2 3 factorial chemical exposure experiment is considered here.
Keywords:Analysis Of Means  Bonferroni Method  Chemical Mixtures  2P Factorial Experiments  Kimball Inequality  Parathion  Star Plot  Yates Algorithm
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