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POEMS综合征合并肺动脉高压临床分析
引用本文:刘淑芬,朱卫国,曾学军,许文兵. POEMS综合征合并肺动脉高压临床分析[J]. 基础医学与临床, 2011, 31(5)
作者姓名:刘淑芬  朱卫国  曾学军  许文兵
作者单位:1. 中国医学科学院,北京协和医学院,北京协和医院,普通内科,北京,100730
2. 中国医学科学院,北京协和医学院,北京协和医院,呼吸内科,北京,100730
摘    要:目的 分析POEMS综合征合并肺动脉高压患者的临床特点.方法 回顾性分析北京协和医院确诊POEMS综合征患者的临床资料,并将超声心动图证实合并肺动脉高压的患者与肺动脉压正常的患者以及未行超声心动检查的患者的临床表现进行比较,描述合并肺动脉高压的POEMS综合征患者的临床特点.结果 POEMS综合征117例,合并肺动脉高压49例,肺动脉压正常33例,未行超声心动检查35例;肺动脉高压患病率41.9%.肺动脉高压组临床表现主要为胸闷、憋气,发生率42.9%(21/49),显著高于另外两组(P≤0.05),但一半以上患者无明显胸闷、憋气;肺动脉高压组并发胸水、腹水、心包积液发生率较另外两组高(P≤0.01),其他临床表现无显著差异.结论 POEMS综合征超声心动图检测肺动脉高压患病率高达40%以上,但半数以上患者无胸闷、憋气,提示在POEMS综合征诊治过程中应重视肺动脉高压的筛查和早期发现.

关 键 词:POEMS综合征  肺动脉高压  超声心动图

Clinical analysis of POEMS syndrome with pulmonary arterial hypertension
LIU Shu-fen,ZHU Wei-guo,ZENG Xue-jun,XU Wen-bing. Clinical analysis of POEMS syndrome with pulmonary arterial hypertension[J]. Basic Medical Sciences and Clinics, 2011, 31(5)
Authors:LIU Shu-fen  ZHU Wei-guo  ZENG Xue-jun  XU Wen-bing
Affiliation:LIU Shu-fen1,ZHU Wei-guo1,ZENG Xue-jun1,XU Wen-bing2(1.Division of General Internal Medicine,2.Devision of Pulmonary Medicine,PUMC Hospital,CAMS & PUMC,Beijing,100730,China)
Abstract:Objective To describe the clinical characteristics of POEMS syndrome associated with pulmonary arterial hypertension.Methods Medical records of patients with POEMS syndrome who were diagnosed in Peking Union Medical College Hospital were reviewed.The clinical manifestations of patients complicated with PAH(pulmonary arterial hypertension,PAH) diagnosed by echocardiography(uCG) was compared with those without PAH and those without echocradiography results.Results One hundred and seventeen patients with POEMS...
Keywords:POEMS syndrome  pulmonary arterial hypertension  echocardiography  
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