| 正常人眼与中,青年原发性开角型青光眼小梁网... |
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| 引用本文： | 易玉珍 张洁. 正常人眼与中,青年原发性开角型青光眼小梁网...[J]. 中华眼科杂志, 1990, 26(4): 213-215 |
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| 作者姓名： | 易玉珍 张洁 |
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| 摘 要： |
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| 关 键 词： | 青光眼 开角 小梁网 组织化学 |
An ultrahistochemical study of the trabecular meshwork in normal and open-angle glaucomatous eyes |
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| Y Z Yi. An ultrahistochemical study of the trabecular meshwork in normal and open-angle glaucomatous eyes[J]. Chinese Journal of Ophthalmology, 1990, 26(4): 213-215 |
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| Authors: | Y Z Yi |
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| Affiliation: | Zhongshan Ophthalmic Center, Sun Yat-sen University of Medical Sciences, Guangzhou, Guangdong Province. |
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| Abstract: | The acid mucopolysaccharides (AMPs) in the human trabecular meshwork were studied ultrahistochemically with hyaluronidase and chondroitinase ABC digestion in 15 normal eyes and 27 cases of primary open-angle glaucoma (POAG). It was found that in normal eyes, hyaluronidase-sensitive AMPs existed in the connective tissue of cribriform meshwork and trabeculae. They could play an important role in regulating the aqueous outflow resistance. In POAG, the amount of AMPs in the trabecular meshwork was increased, leading to increased aqueous outflow resistance through the combination of hyaluronic acid with water, forming electron-dense "plaque" materials in a matrix of chondroitin sulfate. |
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