| 人视网膜母细胞瘤细胞系SO—Rb50的建立及其生物学特征 |
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| 引用本文： | 金捷 区宝祥. 人视网膜母细胞瘤细胞系SO—Rb50的建立及其生物学特征[J]. 中华眼科杂志, 1990, 26(6): 355-359 |
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| 作者姓名： | 金捷 区宝祥 |
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| 摘 要： |
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| 关 键 词： | Rb 眼肿瘤 细胞系 染色体畸变 |
Establishment and characterization of a human retinoblastoma cell line SO-Rb50 |
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| Y Z Yi,J Jie. Establishment and characterization of a human retinoblastoma cell line SO-Rb50[J]. Chinese Journal of Ophthalmology, 1990, 26(6): 355-359 |
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| Authors: | Y Z Yi J Jie |
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| Affiliation: | Zhongshan Ophthalmic Center, Cancer Institute, Sun Yat-sen University of Medical Sciences, Guangzhou. |
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| Abstract: | A human retinoblastoma (Rb) continuous cell line SO-Rb 50 was first established in China from an original tumor of a Chinese baby girl who had no family history of Rb. 33 days after initial culturing, SO-Rb 50 was subcultured and transfers have been made for over 23 months. The SO-Rb 50 cells grow in suspension as clusters with ring formation; their histopathologic and ultrastructural pictures demonstrated characteristics of Rb and were positive to NSE and negative to GFAP in immunohistochemical staining. Heterotransplantation of the cells into NC athymic nude mice was successful in 1/6 of the mice. |
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