四相鼻阻力测量法评估健康成人鼻腔通气状况的初步研究

目的 研究四相鼻阻力测量(four-phase rhinomanometry)法对评估健康成人鼻腔通气状况的临床应用价值.方法 健康成人85名,采用四相鼻阻力计测量吸气、呼气及整个呼吸过程中的有效阻力(effective resistance in inspiration,expiration and total breathing process,分别简称为Reffin、Reffex、Refft),以及吸气和呼气过程的顶点阻力(vertex resistance in inspiration and expiration process,分别简称为Vrin、Vrex).同时,应用鼻声反射仪测量鼻腔的最小横截面积(minimum cross-sectional area of nasal cavity,MCA)和0～5 cm的鼻腔容积(nasal volume from 0-5 cm,V5).对四项鼻阻力和鼻声反射测量结果 进行相关性分析.结果 健康成人男性和女性Reffin(x-±s)分别为(1.28±1.02)Pa/(cm3·s)和(1.55±1.03)Pa/(cm3·s);Reffex(x-±s)分别为(1.43±1.07)Pa/(cm3·s)和(1.75±1.14)Pa/(cm3·s);Refft(x-±s)分别为(1.34±0.99)Pa/(cm3·s)和(1.62±1.03)Pa/(cm3·s);Vrin(x-±s)分别为(1.31±1.03)Pa/,(cm3·s)和(1.60±1.03 Pa/(cm3·s);Vrex(x-±s)分别为(1.46±1.04)Pa/(cm3·s)和(1.82±1.17)Pa/(cm3·s),男性和女性的各观察值比较差异均无统计学意义(r值分别为:0.661、-0.397、0.127、0.649、-0.684,P值均>0.05).Reffin,Reffex,Refft,Vrin和Vrex,与年龄、身高、体重、头围、体表面积、体重指数之间均无显著的相关性(P值均>0.05).Reffin,Reffex,Refft,Vrin,Vrex与MCA、V5之间均有显著的相关性(r值为-0.18～-0.20,P值均<0.05).结论 四相鼻阻力测量的结果 与鼻声反射的测量结果 相关性良好,可作为评估成人鼻腔通气功能的临床检测手段.

Correlation between four-phase rhinomanomctry and acoustic rhinometry

Objective To obtain the normal values of four-phase rhinomanometry specific parameters of normal adult Chinese and analyze the correlation between four-phase rhinomanometry and acoustic rhinometry measurement results. Methods Eighty-five normal adults were recruited. The HRR2 four-phase rhinomanometer was used to acquire the effective resistances in inspiration, expiration and total breathing process (Reffin, Reffex, Refft) and vertex resistance in the process of inspiration and expiration (Vrin and Vrex). The Eecovisian acoustic rhinometry was used to measure the minimum cross-sectional area (MCA) and the nasal volume of 0-5 cm nasal cavity (V5). Results Reffin (x-±s) was (1.28±1.02) Pa/(cm3·s) for male, (1.55±1.03) Pa/(cm3·s) for female;Reflex (x-±s) was (1.43±1.07) Pa/(cm3·s) for male, (1.75±1.14) Pa/(cm3·s) for female;Refft (x-±s) was (1.34±0.99) Pa/(cm3·s) for male, (1.62±1.03) Pa/(cm3·s) for female;Vrin (x-±s) was (1.31±1.03) Pa/(cm3·s) for male;(1.60±1.03) Pa/(cm3·s) for female, Vrex (x-±s) was (1.46±1.04) Pa/(cm3·s) for male, (1.82·1.17) Pa/(cm3·s) for female. No statistically significant difference was found between men and women(r=0.661、-0.397、0.127、0.649、-0.684, P>0.05, respectively). There was no significant correlation between Reffin, Reffex, Refft, Vrin, Vrex and age, height, weight, head circumference, body surface area, body mass index (P>0.05, respectively). However, there was significant correlation between Reffin, Reffex, Refft, Vrin, Vrex and MCA, V5 (P<0.05, respectively). Conclusions The results of four-phase rhinomanometry show significant correlation to acoustic rhinometry.