| 二甲双胍与不同分子亚型乳腺癌的关系 |
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| 引用本文： | 李林(综述),李志高(审校). 二甲双胍与不同分子亚型乳腺癌的关系[J]. 实用肿瘤学杂志, 2018, 32(3): 267-270. DOI: 10.11904/j.issn.1002-3070.2018.03.016 |
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| 作者姓名： | 李林(综述) 李志高(审校) |
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| 作者单位： | 哈尔滨医科大学附属肿瘤医院乳腺外科二病区(哈尔滨 150081) |
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| 基金项目： | 海燕科研基金(编号:JJZD2016-05) |
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| 摘 要： | 二甲双胍做为糖尿病治疗的一线用药,不仅可以降低血糖,还能促使乳腺癌细胞凋亡。体内外实验证实了二甲双胍对各型乳腺癌的抑制作用,而且二甲双胍还能在新辅助化疗以及放疗中协同治疗乳腺癌。本文将对二甲双胍在乳腺癌治疗中的研究进展做一综述。
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| 关 键 词： | 二甲双胍 乳腺癌 治疗 |
| 收稿时间： | 2018-01-07 |
The relationship between metformin and different molecular subtypes of breast cancer |
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| LI Lin,LI Zhigao. The relationship between metformin and different molecular subtypes of breast cancer[J]. Journal of Practical Oncology, 2018, 32(3): 267-270. DOI: 10.11904/j.issn.1002-3070.2018.03.016 |
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| Authors: | LI Lin LI Zhigao |
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| Affiliation: | Department of Oncology,Harbin Medical University Cancer Hospital,Harbin 150081,China |
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| Abstract: | Metformin as the first-line medication for diabetes treatment can not only reduce blood sugar,but it also induces apoptosis in breast cancer cells.The effect and mechanism of metformin on various types of breast cancer are confirmed by in vitro and in vivo,and metformin can also co-treat breast cancer in neoadjuvant chemotherapy and radiotherapy.This article will review the progress of metformin in the treatment of breast cancer. |
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| Keywords: | Metformin Breast cancer Treatment |
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