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对SARS抗体动态水平的系统观察
引用本文:李洪敏,王巍,应希堂,刘冉,林明贵,严黎黎,李燕峰,金来. 对SARS抗体动态水平的系统观察[J]. 中国现代医学杂志, 2004, 14(20): 59-60,63
作者姓名:李洪敏  王巍  应希堂  刘冉  林明贵  严黎黎  李燕峰  金来
作者单位:1. 解放军309医院,结核中心实验室,北京,100091
2. 北京北气东雅生物技术研究所,北京,100012
摘    要:目的应用化学发光光度分析法对SARS抗体(SARS-Ab)动态水平进行观察.方法对432例SARS病人在恢复期的不同阶段进行检测.结果显示SARS病人的抗体检出率为94.0%(404/432).病人SARS-Ab在2,3,4周和2个月时,抗体检出平均光子数值为3.79,7.71,12.31和24.17;3~8个月SARS-Ab下降率分别为92.9%,83.3%,40.0%,26.7%,13.3%和7.0%.结论病人在患病初期,SARS-Ab呈上升趋势,3个月后逐渐下降,并能动态观察不同年龄组SARS-Ab的明显差异.

关 键 词:发光分析法  定量分析
文章编号:1005-8982(2004)20-0059-02

Research of SARS-Ab development condition observation
LI Hong-min,WANG Wei,YING Xi-tang,LIU Ran,LING Min-gui,YAN Li-li,LI Yan-feng,JING Lai. Research of SARS-Ab development condition observation[J]. China Journal of Modern Medicine, 2004, 14(20): 59-60,63
Authors:LI Hong-min  WANG Wei  YING Xi-tang  LIU Ran  LING Min-gui  YAN Li-li  LI Yan-feng  JING Lai
Affiliation:LI Hong-min1,WANG Wei1,YING Xi-tang2,LIU Ran2,LING Min-gui1,YAN Li-li1,LI Yan-feng1,JING Lai1
Abstract:Objective: To study the development condition of SARS antibody analyzed by luminiferous chemoluminescence and examine antibodies of 432 SARS patients in different convalescence. Methods: 432 patients with SARS after treatment their recovering stage were detected. Results: 94 percent of the antibodies of SARS patients were positive (404/432); the average value of the antibody were respectively 3.79,7.71,12.31, after 2 weeks, 3 weeks and 2 months that the patients had suffered from ill, whereas, after 3~8 months, decrease ratio of SARS-Ab were respectively 92.9%, 83.3%, 40.0%, 26.7%, 13.3%, 7.0%. Conclusions: The study indicates that SARS-Ab has increased in initial stage of suffering from SARS, while SARS-Ab has gradually declined after 3 months and we are able to observe obvious difference of SARS-Ab in two groups.
Keywords:SARS-Ab
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