全身炎症反应综合征对急性胰腺炎预后的影响

目的：探讨全身炎症反应综合征（ＳＩＲＳ）对急性胰腺炎预后的影响。方法２３例非手术治疗的急性胰腺炎患者，按是否伴有ＳＩＲＳ，分为ＳＩＲＳ组（１５例）和非ＳＩＲＳ组（８例），对其合并脏器功能障碍、病程及死亡率进行前瞻性观察。结果：ＳＩＲＳ组和非ＳＩＲＳ组器官功能障碍发生率分别为７３．３％和１２．５％（Ｐ＜０．０５）；ＳＩＲＳ组的死亡率为２０％，而非ＳＩＲＳ组无一例死亡；ＳＩＲＳ组平均住院日也显著高于非ＳＩＲＳ组（Ｐ＜０．０５）。结论：ＳＩＲＳ对急性胰腺炎的预后呈显著负性影响，并使病程延长，住院费用增加。

Effects of Systemic Inflammatory Response Syndrome on the Prognosis of Acute Pancreatitis

Background/Aims: To study the effects of systemic inflammatory response syndrome (SIRS) on the prognosis of acute pancreatitis. Methods: Twenty-three non-operated patients with acute pancreatitis were included in the investigation. They were divided into SIRS group (n=15) and non-SIRS group (n=8) according to the diagnotic criteria of SIRS. Organ dysfunction, courses, and mortality in each group were observed prospectively. Results: Morbidity of organ dysfunction in SIRS group were significantly higher than that of non-SIRS group (73.3% vs 12.5%, P<0.05). Mortality in SIRS group was 20%, and no death among non-SIRS group. The mean duration of hospital stay in SIRS group was also significantly longer than that of non-SIRS group. Conclusions: SIRS has a prominently negative effect on the prognosis of acute pancreatitis. SIRS will prolong the course of illness and increase the costs.