| 棉酚治疗子宫肌瘤的临床观察 |
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| 引用本文： | 陈静坤 曹霖. 棉酚治疗子宫肌瘤的临床观察[J]. 上海交通大学学报(医学版), 1997, 17(1): 37-39 |
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| 作者姓名： | 陈静坤 曹霖 |
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| 作者单位： | 上海第二医科大学附属瑞金医院妇产科!200025(陈静坤，金毓翠，李慧芳)，上海市药物研究所!200031(曹霖) |
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| 摘 要： | 醋酸棉酚治疗子宫肌瘤39例，同时以安宫黄体酮对照治疗14例。结果：总有效率醋酸棉酚组为87.18％，安宫黄体酮组为50％，两者差异显著（P＜0．01）。对15例应用棉酚者于用药前后测定血PRL、FSH、LH、E2、P，结果表明子宫肌瘤的缩小及其复发与FSH、LH、E2、P的变化有关，而与PRL关系不大，此项检测可用以判断疗效及预测是否复发。
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| 关 键 词： | 醋酸棉酚 安宫黄体酮 子宫肌瘤 |
Clinical Observations of Uterine Fibromyoma with Gossypol Therapy |
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| Chen Jingkun, Cao Lin, Jin Yucui,et al. Clinical Observations of Uterine Fibromyoma with Gossypol Therapy[J]. Journal of Shanghai Jiaotong University:Medical Science, 1997, 17(1): 37-39 |
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| Authors: | Chen Jingkun Cao Lin Jin Yucui et al |
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| Abstract: | Thirty- nine cases of uterine fibromyoma treated with gossypol were compared with 14 cases of the same disease treated with medroxy-progesterone. The total effective rate of the former was 87.18%, while the latter was 50%. The significant difference was existed between two groups (P<0.01). The investigation of serum PRL, FSH, LH, E, and P in 15 cases pre-and post - application of the gossypol used to evaluate and predict the effectiveness of the therapy and the possibility of recurrence. The result revealed that the shrunk and recurrence of the fibromyoma had closely related with the change of serum levels of FSH, LH, E2 and P, but not too much with PRL. |
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| Keywords: | gossypol fibromyoma medroxy-progesterone |
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